TargetMol

Bedaquiline

Product Code:
 
TAR-T2585
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2585-5mg5mg£108.00
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TAR-T2585-1mL1 mL * 10 mM (in DMSO)£117.00
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TAR-T2585-10mg10mg£128.00
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TAR-T2585-25mg25mg£161.00
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TAR-T2585-50mg50mg£195.00
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TAR-T2585-100mg100mg£230.00
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Quantity:
TAR-T2585-500mg500mg£466.00
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This product comes from: United States.
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Further Information

Bioactivity:
Bedaquiline(TMC207; R207910) is an anti-tuberculosis drug which selectively inhibit the mycobacterial energy metabolism i.e. ATP synthesis and found to be effective against all states of Mycobacterium tuberculosis.
CAS:
843663-66-1
Formula:
C32H31BrN2O2
Molecular Weight:
555.516
Pathway:
Microbiology/Virology
Purity:
0.998
SMILES:
COc1nc2ccc(Br)cc2cc1[C@@H](c1ccccc1)[C@@](O)(CCN(C)C)c1cccc2ccccc12
Target:
Antibacterial; Antibiotic

References

1. Jang JC, et al. Bedaquiline susceptibility test for totally drug-resistant tuberculosis Mycobacterium tuberculosis. J Microbiol. 2017 Apr 20. 2. Pang Y, et al. In Vitro Activity of Bedaquiline against Nontuberculous Mycobacteria in China. Antimicrob Agents Chemother. 2017 Apr 24;61(5). 3. Chahine EB, et al. Bedaquiline: a novel diarylquinoline for multidrug-resistant tuberculosis. Ann Pharmacother. 2014 Jan;48(1):107-15. 4. Wang G, Dong W, Lu H, et al. Enniatin A1, A Natural Compound with Bactericidal Activity against Mycobacterium tuberculosis In Vitro[J]. Molecules. 2020, 25(1): 38.