TargetMol

Palmitoyl rhizoxin

Product Code:
 
TAR-T25917
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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TAR-T25917-5mg5mg£850.00
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Further Information

Bioactivity:
Palmitoyl rhizoxin is a highly lipophilic antitumor compound.
CAS:
135819-69-1
Formula:
C51H77NO10
Molecular Weight:
864.174
Purity:
0.98
SMILES:
[H][C@@]12C[C@@]3([H])CC(=O)O[C@@]([H])(C3)[C@H](C)C=C[C@]3([H])O[C@]3(C)[C@H](C[C@@H](OC(=O)[C@@]1([H])O2)[C@H](C)[C@H](OC)C(C)=CC=CC(C)=Cc1coc(C)n1)OC(=O)CCCCCCCCCCCCCCC

References

1. Kurihara A, Shibayama Y, Mizota A, Yasuno A, Ikeda M, Hisaoka M. Pharmacokinetics of highly lipophilic antitumor agent palmitoyl rhizoxin incorporated in lipid emulsions in rats. Biol Pharm Bull. 1996 Feb;19(2):252-8. PubMed PMID: 8850317. 2. Tokui T, Kuroiwa C, Tokui Y, Sasagawa K, Kawai K, Kobayashi T, Ikeda T, Komai T. Contribution of serum lipoproteins as carriers of antitumour agent RS-1541 (palmitoyl rhizoxin) in mice. Biopharm Drug Dispos. 1994 Mar;15(2):93-107. PubMed PMID: 8011970. 3. Kurihara A, Shibayama Y, Kasuya A, Ikeda M, Hisaoka M. Species variation in pharmacokinetics and opsonization of palmitoyl rhizoxin (RS-1541) incorporated in lipid emulsions. J Drug Target. 1998;5(6):491-505. PubMed PMID: 9783680. 4. Kurihara A, Shibayama Y, Mizota A, Yasuno A, Ikeda M, Sasagawa K, Kobayashi T, Hisaoka M. Enhanced tumor delivery and antitumor activity of palmitoyl rhizoxin using stable lipid emulsions in mice. Pharm Res. 1996 Feb;13(2):305-10. PubMed PMID: 8932454.