TargetMol

p-DDAP

Product Code:
 
TAR-T25925
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25925-5mg5mg£850.00
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TAR-T25925-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T25925-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
p-DDAP is an anti-invasive agent that acts by significantly suppressing cell invasion, and the activity and mRNA expression of matrix metalloproteinase-9 (MMP-9).
CAS:
25848-37-7
Formula:
C18H31NO
Molecular Weight:
277.452
Purity:
0.98
SMILES:
CCCCCCCCCCCCNc1ccc(O)cc1

References

1. Takahashi N, Koyama S, Hasegawa S, Yamasaki M, Imai M. Anticancer efficacy of p-dodecylaminophenol against high-risk and refractory neuroblastoma cells in vitro and in vivo. Bioorg Med Chem Lett. 2017 Oct 15;27(20):4664-4672. doi: 10.1016/j.bmcl.2017.09.005. Epub 2017 Sep 9. PubMed PMID: 28927789. 2. Takahashi N, Egawa R, Imai M, Takahashi K, Ohba T, Imaizumi M. The anti-tumor agent, p-DDAP potently suppresses proliferation through apoptosis in human neuroblastoma NB-39-nu cells. Cancer Lett. 2010 Nov 28;297(2):252-8. doi: 10.1016/j.canlet.2010.05.018. Epub 2010 Jun 26. PubMed PMID: 20580487. 3. Takahashi N, Fujiu Y. Effects of the aminophenol analogue p-Dodecylaminophenol on mouse skin. J Invest Dermatol. 2010 May;130(5):1258-67. doi: 10.1038/jid.2009.386. Epub 2009 Dec 24. PubMed PMID: 20032991. 4. Takahashi N, Watanabe Y, Maitani Y, Yamauchi T, Higashiyama K, Ohba T. p-Dodecylaminophenol derived from the synthetic retinoid, fenretinide: antitumor efficacy in vitro and in vivo against human prostate cancer and mechanism of action. Int J Cancer. 2008 Feb 1;122(3):689-98. PubMed PMID: 17955489.