TargetMol

Riparin III

Product Code:
 
TAR-T26091
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T26091-5mg5mg£850.00
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Further Information

Bioactivity:
Riparin III is an alcamide isolated from Aniba riparia that has exhibited effects of antidepressant and anxiolytic activities in acute stress behavioral models.
CAS:
112356-54-4
Formula:
C16H17NO4
Molecular Weight:
287.315
Purity:
0.98
SMILES:
COc1ccc(CCNC(=O)c2c(O)cccc2O)cc1

References

1. Vasconcelos AS, Oliveira IC, Vidal LT, Rodrigues GC, Gutierrez SJ, Barbosa-Filho JM, Vasconcelos SM, de Fran?a Fonteles MM, Gaspar DM, de Sousa FC. Subchronic administration of riparin III induces antidepressive-like effects and increases BDNF levels in the mouse hippocampus. Fundam Clin Pharmacol. 2015 Aug;29(4):394-403. doi: 10.1111/fcp.12120. Epub 2015 Apr 24. Erratum in: Fundam Clin Pharmacol. 2017 Aug;31(4):481. Vidal, LT [corrected to Vidal, LM]. PubMed PMID: 25846646. 2. Garcia DC, Pereira AC, Gutierrez SJ, Barbosa-Filho JM, Lemos VS, C?rtes SF. Structure-related blockage of calcium channels by vasodilator alkamides in mice mesenteric artery. Vascul Pharmacol. 2016 Jul;82:60-5. doi: 10.1016/j.vph.2016.05.001. Epub 2016 May 10. PubMed PMID: 27173831. 3. Melo CT, de Carvalho AM, Moura BA, Teixeira CP, Vasconcelos LF, Feitosa ML, de Oliveira GV, Barbosa-Filho JM, Chavez Gutierrez SJ, de Fran?a Fonteles MM, Vasconcelos SM, de Sousa FC. Evidence for the involvement of the serotonergic, noradrenergic, and dopaminergic systems in the antidepressant-like action of riparin III obtained from Aniba riparia (Nees) Mez (Lauraceae) in mice. Fundam Clin Pharmacol. 2013 Feb;27(1):104-12. doi: 10.1111/j.1472-8206.2011.00968.x. Epub 2011 Jul 27. PubMed PMID: 21793900. 4. de Melo CT, Monteiro AP, Leite CP, de Ara?jo FL, Lima VT, Barbosa-Filho JM, de Fran?a Fonteles MM, de Vasconcelos SM, de Barros Viana GS, de Sousa FC. Anxiolytic-like effects of (O-methyl)-N-2,6-dihydroxybenzoyl-tyramine (riparin III) from Aniba riparia (Nees) Mez (Lauraceae) in mice. Biol Pharm Bull. 2006 Mar;29(3):451-4. PubMed PMID: 16508144.