TargetMol

SR 43845

Product Code:
 
TAR-T26220
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T26220-5mg5mg£850.00
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  • Further Information
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Further Information

Bioactivity:
SR 43845 is an inhibitor of renin.
CAS:
114037-60-4
Formula:
C44H64N8O8
Molecular Weight:
833.044
Purity:
0.98
SMILES:
CC[C@@H](C)[C@H](NC(=O)C[C@@H](O)[C@@H](CC1CCCCC1)NC(=O)[C@@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CCc1cccnc1)C(=O)NC(C)(CO)CO

References

1. Lacour C, Cazaubon C, Roccon A, Segondy D, Wagnon J, Nisato D. Effects of a renin inhibitor, SR 43845, and of captopril on blood pressure and plasma active renin in conscious sodium-replete macaca. J Hypertens Suppl. 1989 Apr;7(2):S33-5. PubMed PMID: 2666612. 2. Cazaubon C, Richaud JP, Nisato D. [A new method for determination of renin inhibitors]. Arch Mal Coeur Vaiss. 1990 Jul;83(8):1267-70. French. PubMed PMID: 2124466. 3. Denolle T, Luo P, Guyene TT, Cazaubon C, Sissmann J, Corvol P, M?nard J. Acute effects of a pseudo-tetrapeptide as renin inhibitor on blood pressure and renin-angiotensin system of sodium-repleted and sodium-depleted hypertensive patients. Arzneimittelforschung. 1993 Feb;43(2A):255-9. PubMed PMID: 8498973. 4. Cohen P, Simon D, Badouaille G, Mani JC, Portefaix JM, Pau B. New monoclonal antibodies directed against the propart segment of human prorenin as a tool for the exploration of prorenin conformation. J Immunol Methods. 1995 Jul 17;184(1):91-100. PubMed PMID: 7622873.