TargetMol

Tetrahydrohomofolic acid

Product Code:
 
TAR-T26261
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26261-5mg5mg£1,572.00
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TAR-T26261-50mg50mg£3,107.00
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Quantity:
TAR-T26261-100mg100mg£4,247.00
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This product comes from: United States.
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Further Information

Bioactivity:
Tetrahydrohomofolic acid is a thymidylate synthetase inhibitor, antibacterial, and antimalarial agent.
CAS:
5786-82-3
Formula:
C20H25N7O6
Molecular Weight:
459.463
Purity:
0.98
SMILES:
Nc1nc(O)c2NC(CCNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)CNc2n1

References

1. Slieker LJ, Benkovic SJ. Inhibition of HKSV28 cell growth by 5,11-methenyl-tetrahydrohomofolate. Mol Pharmacol. 1984 Mar;25(2):294-302. PubMed PMID: 6700575. 2. Wasserman GF, Benkovic PA, Young M, Benkovic SJ. Kinetic relationships between the various activities of the formyl-methenyl-methylenetetrahydrofolate synthetase. Biochemistry. 1983 Mar 1;22(5):1005-13. PubMed PMID: 6601493. 3. Fong KL, Ho DH, Benjamin RS, Yang F, Sickler J, Brown NS, Bodey GP. A radioimmunoassay for 5-methyltetrahydrohomofolate. J Pharmacol Exp Ther. 1981 Aug;218(2):344-7. PubMed PMID: 6265623. 4. Mishra LC, Mead JA. On the biochemical mechanism of action of tetrahydrohomofolic acid. Biochem Pharmacol. 1972 Feb 15;21(4):579-81. PubMed PMID: 5014514.