TargetMol

Tubulozole

Product Code:
 
TAR-T26299
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26299-5mg5mg£850.00
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TAR-T26299-50mg50mg£1,661.00
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Quantity:
TAR-T26299-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Tubulozole is a microtubule inhibitor. It inhibits microtubule dynamics required for proper mitotic function, effectively blocking cell cycle progression and resulting in apoptosis.
CAS:
84697-22-3
Formula:
C23H23Cl2N3O4S
Molecular Weight:
508.41
Purity:
0.98
SMILES:
CCOC(=O)Nc1ccc(SC[C@H]2CO[C@@](Cn3ccnc3)(O2)c2ccc(Cl)cc2Cl)cc1

References

1. Servely JL, Geuens GM, Martel P, Houdebine LM, de Brabander M. Effect of tubulozole, a new synthetic microtubule inhibitor, on the induction of casein gene expression by prolactin. Biol Cell. 1987;59(2):121-7. PubMed PMID: 2957009. 2. Geuens GM, Nuydens RM, Willebrords RE, Van de Veire RM, Goossens F, Dragonetti CH, Mareel MM, De Brabander MJ. Effects of tubulozole on the microtubule system of cells in culture and in vivo. Cancer Res. 1985 Feb;45(2):733-42. PubMed PMID: 3967244. 3. Fong D. Effect of the anti-microtubule compound tubulozole on Leishmania protozoan parasites in vitro. FEMS Microbiol Lett. 1993 Feb 15;107(1):95-9. PubMed PMID: 8468004. 4. Distelmans W, Van Ginckel R, Vanherck W, Willebrords R, De Brabander M, Wouters L, Van den Winkel P, De Backer G. Interaction between the microtubule inhibitor tubulozole and gamma-irradiation in murine tumors in vivo. Int J Radiat Oncol Biol Phys. 1989 Jan;16(1):177-82. PubMed PMID: 2912940.