TargetMol

A 201A

Product Code:
 
TAR-T26405
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26405-5mg5mg£850.00
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Further Information

Bioactivity:
A 201A is a nucleoside antibiotic, it is isolated from Streptomyces capreolus.
CAS:
37305-78-5
Formula:
C37H50N6O14
Molecular Weight:
802.835
Purity:
0.98
SMILES:
COC1C(C)OC(OCC(OC)=C2OC(Oc3ccc(C=C(/C)C(=O)NC4C(CO)OC(C4O)n4cnc5c(ncnc45)N(C)C)cc3)C(O)C2O)C(O)C1OC

References

1. Nie S, Li W, Yu B. Total synthesis of nucleoside antibiotic A201A. J Am Chem Soc. 2014 Mar 19;136(11):4157-60. doi: 10.1021/ja501460j. Epub 2014 Mar 11. PubMed PMID: 24611434. 2. Nie S, Chen X, Ma Y, Li W, Yu B. An unexpected rearrangement of pent-4-enofuranosides to cyclopentanones upon hydrogenolysis of the anomeric benzyl group. Carbohydr Res. 2016 Sep 2;432:36-40. doi: 10.1016/j.carres.2016.06.006. Epub 2016 Jun 18. PubMed PMID: 27366975. 3. Kirst HA, Dorman DE, Occolowitz JL, Jones ND, Paschal JW, Hamill RL, Szymanski EF. The structure of A201A, a novel nucleoside antibiotic. J Antibiot (Tokyo). 1985 May;38(5):575-86. PubMed PMID: 4019309. 4. Zhu Q, Li J, Ma J, Luo M, Wang B, Huang H, Tian X, Li W, Zhang S, Zhang C, Ju J. Discovery and engineered overproduction of antimicrobial nucleoside antibiotic A201A from the deep-sea marine actinomycete Marinactinospora thermotolerans SCSIO 00652. Antimicrob Agents Chemother. 2012 Jan;56(1):110-4. doi: 10.1128/AAC.05278-11. Epub 2011 Nov 7. PubMed PMID: 22064543; PubMed Central PMCID: PMC3256081.