TargetMol

A 70450

Product Code:
 
TAR-T26435
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26435-5mg5mg£1,653.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T26435-50mg50mg£3,267.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T26435-100mg100mg£4,488.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
A 70450, an inhibitor of aspartyl proteinase, can be used as an antifungal agent and may have a role in HIV protease inhibition therapy.
CAS:
142928-23-2
Formula:
C19H39ClN2O2
Molecular Weight:
362.98
Purity:
0.98
SMILES:
Cl.CCCCNC(=O)[C@H](C[C@H](O)[C@@H](N)CC1CCCCC1)C(C)C

References

1. Stewart K, Abad-Zapatero C. Candida proteases and their inhibition: prospects for antifungal therapy. Curr Med Chem. 2001 Jul;8(8):941-8. Review. PubMed PMID: 11375761. 2. Pranav Kumar SK, Kulkarni VM. Insights into the selective inhibition of Candida albicans secreted aspartyl protease: a docking analysis study. Bioorg Med Chem. 2002 Apr;10(4):1153-70. PubMed PMID: 11836127. 3. Cutfield SM, Dodson EJ, Anderson BF, Moody PC, Marshall CJ, Sullivan PA, Cutfield JF. The crystal structure of a major secreted aspartic proteinase from Candida albicans in complexes with two inhibitors. Structure. 1995 Nov 15;3(11):1261-71. PubMed PMID: 8591036. 4. Abad-Zapatero C, Goldman R, Muchmore SW, Hutchins C, Oie T, Stewart K, Cutfield SM, Cutfield JF, Foundling SI, Ray TL. Structure of secreted aspartic proteinases from Candida. Implications for the design of antifungal agents. Adv Exp Med Biol. 1998;436:297-313. Review. PubMed PMID: 9561233.