A 71915

Product Code:

TAR-T26437

Product Group:

Inhibitors and Activators

Supplier:

TargetMol

Regulatory Status:

RUO

Shipping:

cool pack

Storage:

-20℃

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Code	Size	Price

TAR-T26437-5mg

5mg

£390.00

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Quantity:

Prices exclude any Taxes / VAT

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Further Information

Bioactivity:

A 71915, an atrial natricuretic factor receptor antagonist, blocks physiological effects of angiotensin.

CAS:

132956-87-7

Formula:

C69H116N26O15S2

Molecular Weight:

1613.97

Purity:

0.98

SMILES:

CC[C@H](C)[C@@H]1NC(=O)[C@@H](CCCNC(N)=N)NC(=O)CNC(=O)CNC(=O)[C@H](CC2CCCCC2)NC(=O)[C@H](CSS[C@H](CCCNC(N)=N)[C@H](NC(=O)CNC(=O)[C@H]2Cc3ccccc3CN2C(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC1=O)[C@@H](C)CC)C(N)=O)NC(=O)[C@@H](N)CCCNC(N)=N

Documents

References

1. Zhao J, Liu E, Li G, Qi L, Li J, Yang W. Effects of the angiotensin-(1-7)/Mas/PI3K/Akt/nitric oxide axis and the possible role of atrial natriuretic peptide in an acute atrial tachycardia canine model. J Renin Angiotensin Aldosterone Syst. 2015 Dec;16(4):1069-77. doi: 10.1177/1470320314543723. Epub 2014 Aug 20. PubMed PMID: 25143331. 2. Zhao J, Liu T, Liu E, Li G, Qi L, Li J. The potential role of atrial natriuretic peptide in the effects of Angiotensin-(1-7) in a chronic atrial tachycardia canine model. J Renin Angiotensin Aldosterone Syst. 2016 Mar 23;17(1):1470320315627409. doi: 10.1177/1470320315627409. Print 2016 Jan-Mar. PubMed PMID: 27009283. 3. Kiguchi N, Sukhtankar DD, Ding H, Tanaka K, Kishioka S, Peters CM, Ko MC. Spinal Functions of B-Type Natriuretic Peptide, Gastrin-Releasing Peptide, and Their Cognate Receptors for Regulating Itch in Mice. J Pharmacol Exp Ther. 2016 Mar;356(3):596-603. doi: 10.1124/jpet.115.229997. Epub 2015 Dec 15. PubMed PMID: 26669425; PubMed Central PMCID: PMC4767390. 4. Pandey KN, Nguyen HT, Li M, Boyle JW. Natriuretic peptide receptor-A negatively regulates mitogen-activated protein kinase and proliferation of mesangial cells: role of cGMP-dependent protein kinase. Biochem Biophys Res Commun. 2000 May 10;271(2):374-9. PubMed PMID: 10799305.