TargetMol

A 76889

Product Code:
 
TAR-T26445
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26445-5mg5mg£1,332.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T26445-50mg50mg£2,625.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T26445-100mg100mg£3,524.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
A 76889 is an inhibitor of HIV-1 protease.
CAS:
134805-77-9
Formula:
C44H58N8O6
Molecular Weight:
794.998
Purity:
0.98
SMILES:
CC(C)[C@H](NC(=O)N(C)Cc1ccccn1)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)N(C)Cc1ccccn1)C(C)C

References

1. Holzman TF, Kohlbrenner WE, Weigl D, Rittenhouse J, Kempf D, Erickson J. Inhibitor stabilization of human immunodeficiency virus type-2 proteinase dimer formation. J Biol Chem. 1991 Oct 15;266(29):19217-20. PubMed PMID: 1918040. 2. Powell DJ, Bur D, Wlodawer A, Gustchina A, Payne SL, Dunn BM, Kay J. Expression, characterisation and mutagenesis of the aspartic proteinase from equine infectious anaemia virus. Eur J Biochem. 1996 Oct 15;241(2):664-74. Erratum in: Eur J Biochem 1997 May 15;246(1):258. PubMed PMID: 8917470. 3. Gustchina A, Kervinen J, Powell DJ, Zdanov A, Kay J, Wlodawer A. Structure of equine infectious anemia virus proteinase complexed with an inhibitor. Protein Sci. 1996 Aug;5(8):1453-65. PubMed PMID: 8844837; PubMed Central PMCID: PMC2143478. 4. Lee CY, Yang PK, Tzou WS, Hwang MJ. Estimates of relative binding free energies for HIV protease inhibitors using different levels of approximations. Protein Eng. 1998 Jun;11(6):429-37. PubMed PMID: 9725621.