TargetMol

A110

Product Code:
 
TAR-T26463
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26463-5mg5mg£850.00
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Quantity:
TAR-T26463-50mg50mg£1,661.00
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Quantity:
TAR-T26463-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
A110 is a potent and selective IMPDHs inhibitor. It binds to the NAD(+) cofactor site and forms a ternary complex with IMP.
CAS:
1185388-35-5
Formula:
C19H15ClN4O2
Molecular Weight:
366.81
Purity:
0.98
SMILES:
C[C@@H](Oc1cc[n+]([O-])c2ccccc12)c1cn(nn1)-c1ccc(Cl)cc1

References

1. Wei Y, Kuzmi? P, Yu R, Modi G, Hedstrom L. Inhibition of Inosine-5'-monophosphate Dehydrogenase from Bacillus anthracis: Mechanism Revealed by Pre-Steady-State Kinetics. Biochemistry. 2016 Sep 20;55(37):5279-88. doi: 10.1021/acs.biochem.6b00265. Epub 2016 Sep 2. PubMed PMID: 27541177; PubMed Central PMCID: PMC5524190.