TargetMol

A-176120

Product Code:
 
TAR-T26469
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26469-5mg5mg£850.00
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Quantity:
TAR-T26469-50mg50mg£1,661.00
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Quantity:
TAR-T26469-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
A-176120 is a potent farnesyl pyrophosphate (FPP) analogues, it selectively inhibits farnesyltransferase. It has anti-angiogenic potential and may reduce H-ras NIH3T3 tumour growth.
CAS:
185049-54-1
Formula:
C33H29NO9
Molecular Weight:
583.593
Purity:
0.98
SMILES:
CCOc1ccccc1CN(Cc1cccc(Oc2ccc(C)cc2)c1)C(=O)c1cc(C(O)=O)c(cc1C(O)=O)C(O)=O

References

1. Tahir SK, Gu WZ, Zhang HC, Leal J, Lee JY, Kovar P, Saeed B, Cherian SP, Devine E, Cohen J, Warner R, Wang YC, Stout D, Arendsen DL, Rosenberg S, Ng SC. Inhibition of farnesyltransferase with A-176120, a novel and potent farnesyl pyrophosphate analogue. Eur J Cancer. 2000 Jun;36(9):1161-70. PubMed PMID: 10854950.