TargetMol

A1777

Product Code:
 
TAR-T26470
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26470-5mg5mg£1,412.00
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Quantity:
TAR-T26470-50mg50mg£2,785.00
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Quantity:
TAR-T26470-100mg100mg£3,765.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
A1777, a selective 5-lipoxygenase inhibitor, reduces leukocytes proliferation without affecting the eosinophils of mast cells.
CAS:
90316-11-3
Formula:
C21H24O4
Molecular Weight:
340.419
Purity:
0.98
SMILES:
CC1=C(C)C(=O)C(CCCCC#CCCCC#CC(O)=O)=C(C)C1=O

References

1. Tanaka K, Ueno A, Katori M. Roles of leukotrienes in two rat allergic inflammatory models; IgE-mediated and IgG-antigen complex-induced pleurisies. Prostaglandins. 1986 Jun;31(6):1099-116. PubMed PMID: 3020615. 2. Qian J, Steigerwald K, Combs KA, Barton MC, Groden J. Caspase cleavage of the APC tumor suppressor and release of an amino-terminal domain is required for the transcription-independent function of APC in apoptosis. Oncogene. 2007 Jul 19;26(33):4872-6. Epub 2007 Feb 5. PubMed PMID: 17297457. 3. Nagai K, Katori M. Possible changes in the leukocyte membrane as a mechanism of leukocyte adhesion to the venular walls induced by leukotriene B4 and fMLP in the microvasculature of the hamster cheek pouch. Int J Microcirc Clin Exp. 1988 Nov;7(4):305-14. PubMed PMID: 2851564.