TargetMol

AI-4-57 Hydrochloride

Product Code:
 
TAR-T26580
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26580-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T26580-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T26580-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
AI-4-57 Hydrochloride is a ligand to the CBF?. AI-4-57 Hydrochloride is a modest potency inhibitor of the binding of wildtype CBF? to the RUNX1 Runt domain.
CAS:
63053-14-5
Formula:
C13H12ClN3O
Molecular Weight:
261.71
Purity:
0.98
SMILES:
Cl.COc1ccc2[nH]c(nc2c1)-c1ccccn1

References

1. Illendula A, Pulikkan JA, Zong H, et al. A small-molecule inhibitor of the aberrant transcription factor CBF?-SMMHC delays leukemia in mice. Science (New York, NY). 2015;347(6223):779-784. doi:10.1126/science.aaa0314.