TargetMol

AIC-292

Product Code:
 
TAR-T26581
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26581-5mg5mg£930.00
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TAR-T26581-50mg50mg£1,821.00
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Quantity:
TAR-T26581-100mg100mg£2,319.00
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Further Information

Bioactivity:
AIC-292 is a potent reverse transcriptase inhibitor with well tolerated in different cell lines. In addition, activity of AIC292 could be demonstrated against a broad panel of wild-type HIV-1 group. AIC292 also retained activity against viruses harboring NNRTI resistance-associated mutations (RAMs), including the most prevalent variants, K103N, G190A and Y181C.
CAS:
1187917-12-9
Formula:
C19H12Cl2F2N4O2
Molecular Weight:
437.23
Purity:
0.98
SMILES:
Fc1cc(Cl)cc(c1)-c1cc(nn1-c1ccc(F)c(Cl)c1)C(=O)N1CNC(=O)C1

References

1. Wildum S, Paulsen D, Thede K, Ruebsamen-Schaeff H, Zimmermann H. In vitro and in vivo activities of AIC292, a novel HIV-1 nonnucleoside reverse transcriptase inhibitor. Antimicrob Agents Chemother. 2013 Nov;57(11):5320-9. doi: 10.1128/AAC.01377-13. PubMed PMID: 23959304; PubMed Central PMCID: PMC3811302.