TargetMol

Albifylline

Product Code:
 
TAR-T26589
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26589-5mg5mg£850.00
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TAR-T26589-50mg50mg£1,661.00
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Quantity:
TAR-T26589-100mg100mg£2,079.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Albifylline is a xanthine derivates with anti-asthmatic activity. Albifylline may cause a significant reduction of shock-induced leukocyte adhesions to the sinusoidal endothelium in the liver after hemorrhagic shock. Albifylline also improves microvascular blood flow in the liver.
CAS:
107767-55-5
Formula:
C13H20N4O3
Molecular Weight:
280.328
Purity:
0.98
SMILES:
Cn1c2nc[nH]c2c(=O)n(CCCCC(C)(C)O)c1=O

References

1. Marzi I, Maier M, Herzog C, Bauer M. Influence of pentoxifylline and albifylline on liver microcirculation and leukocyte adhesion after hemorrhagic shock in the rat. J Trauma. 1996 Jan;40(1):90-6. PubMed PMID: 8577006. 2. Meskini N, N?moz G, Okyayuz-Baklouti I, Lagarde M, Prigent AF. Phosphodiesterase inhibitory profile of some related xanthine derivatives pharmacologically active on the peripheral microcirculation. Biochem Pharmacol. 1994 Mar 2;47(5):781-8. PubMed PMID: 8135854. 3. Sinha B, Semmler J, Eisenhut T, Eigler A, Endres S. Enhanced tumor necrosis factor suppression and cyclic adenosine monophosphate accumulation by combination of phosphodiesterase inhibitors and prostanoids. Eur J Immunol. 1995 Jan;25(1):147-53. PubMed PMID: 7843225. 4. Sinha B, Semmler J, Haen E, Moeller J, Endres S. Radioimmunoassays for cyclic AMP cross-react with phosphodiesterase inhibitors and buffer components. J Toxicol Methods. 1995 Sep;34(1):29-36. PubMed PMID: 7496044.