TargetMol

ASM-024

Product Code:
 
TAR-T26666
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26666-1mg1mg£278.00
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Quantity:
TAR-T26666-1mL1 mL * 10 mM (in DMSO)£499.00
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TAR-T26666-5mg5mg£586.00
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TAR-T26666-10mg10mg£804.00
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TAR-T26666-25mg25mg£1,171.00
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Quantity:
TAR-T26666-50mg50mg£1,556.00
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Quantity:
TAR-T26666-100mg100mg£2,079.00
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Quantity:
TAR-T26666-500mg500mg£4,006.00
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Further Information

Bioactivity:
ASM-024, a nicotinic receptor agonist, is used potentially for the treatment of asthma and chronic obstructive bronchitis.
CAS:
1609534-88-4
Formula:
C15H25N2
Molecular Weight:
233.378
Pathway:
Neuroscience
Purity:
0.98
SMILES:
CC[N+]1(CC)CCCN(CC1)c1ccccc1
Target:
AChR

References

1. Boulet LP, Gauvreau GM, Cockcroft DW, Davis B, Vachon L, Cormier Y, O'Byrne PM. Effects of ASM-024, a modulator of acetylcholine receptor function, on airway responsiveness and allergen-induced responses in patients with mild asthma. Can Respir J. 2015 Jul-Aug;22(4):230-4. PubMed PMID: 26252534; PubMed Central PMCID: PMC4530857. 2. Isra?l-Assayag E, Beaulieu MJ, Cormier Y. ASM-024, a piperazinium compound, promotes the in vitro relaxation of ?2-adrenoreceptor desensitized tracheas. PLoS One. 2015 Mar 23;10(3):e0120095. doi: 10.1371/journal.pone.0120095. PubMed PMID: 25799096; PubMed Central PMCID: PMC4370676. 3. Watson BM, Oliveria JP, Nusca GM, Smith SG, Beaudin S, Dua B, Watson RM, Assayag EI, Cormier YF, Sehmi R, Gauvreau GM. Inhibition of allergen-induced basophil activation by ASM-024, a nicotinic receptor ligand. Int Arch Allergy Immunol. 2014;165(4):255-64. doi: 10.1159/000370068. PubMed PMID: 25660404. 4. Assayag EI, Beaulieu MJ, Cormier Y. Bronchodilatory and anti-inflammatory effects of ASM-024, a nicotinic receptor ligand, developed for the treatment of asthma. PLoS One. 2014 Jan 22;9(1):e86091. doi: 10.1371/journal.pone.0086091. PubMed PMID: 24465890; PubMed Central PMCID: PMC3899211.