TargetMol

AZD4619

Product Code:
 
TAR-T26716
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26716-5mg5mg£1,091.00
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Quantity:
TAR-T26716-50mg50mg£2,143.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T26716-100mg100mg£2,801.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
AZD4619 is a potent, selective and reversible orally bioavailable agonist of PPARα receptor.
CAS:
1067247-60-2
Formula:
C27H30O6S2
Molecular Weight:
514.65
Purity:
0.98
SMILES:
Cc1ccc(CCSC(Cc2ccc(CCOc3ccc(OS(C)(=O)=O)cc3)cc2)C(O)=O)cc1

References

1. Thulin P, Bamberg K, Buler M, Dahl B, Glinghammar B. The peroxisome proliferator-activated receptor ? agonist, AZD4619, induces alanine aminotransferase-1 gene and protein expression in human, but not in rat hepatocytes: Correlation with serum ALT levels. Int J Mol Med. 2016 Sep;38(3):961-8. doi: 10.3892/ijmm.2016.2681. PubMed PMID: 27430334. 2. Thulin P, Rafter I, Stockling K, Tomkiewicz C, Norjavaara E, Aggerbeck M, Hellmold H, Ehrenborg E, Andersson U, Cotgreave I, Glinghammar B. PPARalpha regulates the hepatotoxic biomarker alanine aminotransferase (ALT1) gene expression in human hepatocytes. Toxicol Appl Pharmacol. 2008 Aug 15;231(1):1-9. doi: 10.1016/j.taap.2008.03.007. PubMed PMID: 18455211.