TargetMol

Azotomycin

Product Code:
 
TAR-T26729
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26729-5mg5mg£1,332.00
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TAR-T26729-50mg50mg£2,625.00
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Quantity:
TAR-T26729-100mg100mg£3,524.00
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This product comes from: United States.
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Further Information

Bioactivity:
Azotomycin is an antagonist of L-glutamine and may be used as an immunosuppressant.
CAS:
7644-67-9
Formula:
C17H23N7O8
Molecular Weight:
453.412
Purity:
0.98
SMILES:
N[C@@H](CCC(=O)N[C@@H](CCC(=O)C=[N+]=[N-])C(=O)N[C@@H](CCC(=O)C=[N+]=[N-])C(O)=O)C(O)=O

References

1. Chang P, Wiernik PH. Phase II study of azotomycin in sarcomas. Cancer Treat Rep. 1977 Dec;61(9):1719-20. PubMed PMID: 340036. 2. Cooney DA, Yavelow J, Zlotoff R, Bergenstal R, Burg A, Morrison R, Fleischman R. Azotomycin--toxicologic, biochemical and pharmacologic studies in mice. Biochem Pharmacol. 1974 Dec 15;23(24):3467-89. PubMed PMID: 4155310. 3. Catane R, Von Hoff DD, Glaubiger DL, Muggia FM. Azaserine, DON, and azotomycin: three diazo analogs of L-glutamine with clinical antitumor activity. Cancer Treat Rep. 1979 Jun;63(6):1033-8. Review. PubMed PMID: 380801. 4. Weiss AJ, Mastrangelo MJ. Phase I study of a combination of azotomycin (NSC-56654) and 5-fluorouracil (NSC-19893) in malignant disease. Cancer Chemother Rep. 1970 Apr;54(2):109-11. PubMed PMID: 4946000.