TargetMol

BAS00127538

Product Code:
 
TAR-T26738
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26738-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T26738-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T26738-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
BAS00127538 is an Lipid II inhibitor.
CAS:
110673-34-2
Formula:
C31H28BF4NO
Molecular Weight:
517.37
Purity:
0.98
SMILES:
F[B-](F)(F)F.C[N+]1=C(C=CC=C2OC(=CC(=C2)c2ccccc2)c2ccccc2)C(C)(C)c2ccccc12

References

1. Chauhan J, Cardinale S, Fang L, Huang J, Kwasny SM, Pennington MR, Basi K, diTargiani R, Capacio BR, MacKerell AD Jr, Opperman TJ, Fletcher S, de Leeuw EP. Towards Development of Small Molecule Lipid II Inhibitors as Novel Antibiotics. PLoS One. 2016 Oct 24;11(10):e0164515. doi: 10.1371/journal.pone.0164515. eCollection 2016. PubMed PMID: 27776124; PubMed Central PMCID: PMC5077133. 2. Pach?n-Ib??ez ME, Smani Y, Pach?n J. Use of adjuvants in the treatment of Acinetobacter baumannii. Expert Rev Anti Infect Ther. 2016;14(2):153-5. doi: 10.1586/14787210.2016.1126508. Epub 2015 Dec 19. PubMed PMID: 26620637. 3. Fletcher S, Yu W, Huang J, Kwasny SM, Chauhan J, Opperman TJ, MacKerell AD Jr, de Leeuw E. Structure-activity exploration of a small-molecule Lipid II inhibitor. Drug Des Devel Ther. 2015 Apr 24;9:2383-94. doi: 10.2147/DDDT.S79504. eCollection 2015. PubMed PMID: 25987836; PubMed Central PMCID: PMC4422293. 4. de Leeuw EP. Efficacy of the small molecule inhibitor of Lipid II BAS00127538 against Acinetobacter baumannii. Drug Des Devel Ther. 2014 Aug 8;8:1061-4. doi: 10.2147/DDDT.S68020. eCollection 2014. PubMed PMID: 25143710; PubMed Central PMCID: PMC4134019.