TargetMol

BAY-Y-5959

Product Code:
 
TAR-T26746
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26746-5mg5mg£930.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T26746-50mg50mg£1,821.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T26746-100mg100mg£2,319.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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  • Further Information
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Further Information

Bioactivity:
BAY-Y-5959, a calcium channel agonist, is used potentially for the treatment of arrhythmia, heart failure and myocardial.
CAS:
146136-94-9
Formula:
C26H24N4O2
Molecular Weight:
424.504
Purity:
0.98
SMILES:
CC(C)OC(=O)C1=C(N)NC(C)=C(C#N)[C@H]1c1cccc2ncc(cc12)-c1ccccc1

References

1. de Haan S, Greiser M, Harks E, Blaauw Y, van Hunnik A, Verheule S, Allessie M, Schotten U. AVE0118, blocker of the transient outward current (I(to)) and ultrarapid delayed rectifier current (I(Kur)), fully restores atrial contractility after cardioversion of atrial fibrillation in the goat. Circulation. 2006 Sep 19;114(12):1234-42. Epub 2006 Aug 28. PubMed PMID: 16940189. 2. Takagi G, Asai K, Vatner SF, Kudej RK, Rossi F, Peppas A, Takagi I, Resuello RR, Natividad F, Shen YT, Vatner DE. Gender differences on the effects of aging on cardiac and peripheral adrenergic stimulation in old conscious monkeys. Am J Physiol Heart Circ Physiol. 2003 Aug;285(2):H527-34. PubMed PMID: 12860563. 3. Schotten U, Duytschaever M, Ausma J, Eijsbouts S, Neuberger HR, Allessie M. Electrical and contractile remodeling during the first days of atrial fibrillation go hand in hand. Circulation. 2003 Mar 18;107(10):1433-9. PubMed PMID: 12642366. 4. Cabo C, Schmitt H, Wit AL. New mechanism of antiarrhythmic drug action: increasing L-type calcium current prevents reentrant ventricular tachycardia in the infarcted canine heart. Circulation. 2000 Nov 7;102(19):2417-25. PubMed PMID: 11067798.