TargetMol

BDF 9148

Product Code:
 
TAR-T26757
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26757-5mg5mg£930.00
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TAR-T26757-50mg50mg£1,821.00
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Quantity:
TAR-T26757-100mg100mg£2,319.00
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Further Information

Bioactivity:
BDF 9148, a Na(+)-channel modulator, increases the contractile force of guinea-pig atria and papillary muscles.
CAS:
120838-62-2
Formula:
C28H27N3O3
Molecular Weight:
453.542
Purity:
0.98
SMILES:
OC(COC1CN(C1)C(c1ccccc1)c1ccccc1)COc1cccc2[nH]c(cc12)C#N

References

1. Brixius K, Hoischen S, Zobel C, Lasek K, Schwinger RH. [The Ca(2+) sensitizers CGP 48506 and EMD 57033, but not the Na(+) channel modulator BDF 9148, prolong relaxation in isolated cardiomyocytes of the guinea pig]. Z Kardiol. 2001 Apr;90(4):286-91. German. PubMed PMID: 11381577. 2. Nand V, Doggrell SA. Effects of BDF 9148 on the action potentials and contractions of left ventricles from normo- and hypertensive rats. Clin Exp Pharmacol Physiol. 1999 Mar;26(3):212-9. PubMed PMID: 10081616. 3. Zobel C, Brixius K, Frank K, Schwinger RH. Effect of the Na+-channel modulator BDF 9148 on Ca2+-sensitivity and force of contraction of hypertrophic myocardium from transgene rats harboring the mouse Renin gene (TG(mREN2)27). Naunyn Schmiedebergs Arch Pharmacol. 1998 May;357(5):532-9. PubMed PMID: 9650806. 4. Doggrell SA, Liang LC. The relaxing effect of BDF 9148 on the KCl-contracted aorta isolated from normo- and hyper-tensive rats. Naunyn Schmiedebergs Arch Pharmacol. 1998 Feb;357(2):126-32. PubMed PMID: 9521485.