TargetMol

BKM1740

Product Code:
 
TAR-T26832
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T26832-25mg25mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
BKM1740 induced apoptosis in prostate cancer (PCa) cells by repressing survivin at both the mRNA and protein levels in vitro.
CAS:
1070966-97-0
Formula:
C39H46Cl2F5N3O9P2
Molecular Weight:
928.65
Purity:
0.98
SMILES:
CCOP(=O)(OCC)C(N1CCC(CC1)NC(=O)[C@H](Cc1ccc(OCc2c(Cl)cccc2Cl)cc1)NC(=O)C=Cc1c(F)c(F)c(F)c(F)c1F)P(=O)(OCC)OCC

Documents

References

1. Seo SI, Gera L, Zhau HE, Qian WP, Iqbal S, Johnson NA, Zhang S, Zayzafoon M, Stewart J, Wang R, Chung LW, Wu D. BKM1740, an acyl-tyrosine bisphosphonate amide derivative, inhibits the bone metastatic growth of human prostate cancer cells by inducing apoptosis. Clin Cancer Res. 2008 Oct 1;14(19):6198-206. doi: 10.1158/1078-0432.CCR-08-1023. PubMed PMID: 18829499.