TargetMol

BNC-1

Product Code:
 
TAR-T26879
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T26879-5mg5mg£850.00
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Quantity:
TAR-T26879-50mg50mg£1,661.00
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Quantity:
TAR-T26879-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
BNC-1 is a modulator of amyloid pathology. BNC-1 significantly decreases amyloid burden and improves markers of synaptic integrity in well-established mouse models of amyloid deposition by promoting phosphorylation and activation of Elk-1.
CAS:
96335-59-0
Formula:
C16H14N2O3
Molecular Weight:
282.299
Purity:
0.98
SMILES:
COC(=O)c1c(C)nc(C)c2c1c1ccccc1[nH]c2=O

References

1. Lovell MA, Lynn BC, Fister S, Bradley-Whitman M, Murphy MP, Beckett TL, Norris CM. A Novel Small Molecule Modulator of Amyloid Pathology. J Alzheimers Dis. 2016 May 4;53(1):273-87. doi: 10.3233/JAD-151160. PubMed PMID: 27163808. 2. Hermanstyne TO, Markowitz K, Fan L, Gold MS. Mechanotransducers in rat pulpal afferents. J Dent Res. 2008 Sep;87(9):834-8. PubMed PMID: 18719209; PubMed Central PMCID: PMC2577312. 3. Wang J, Zhang S, Schultz RM, Tseng H. Search for basonuclin target genes. Biochem Biophys Res Commun. 2006 Oct 6;348(4):1261-71. Epub 2006 Aug 10. PubMed PMID: 16919236; PubMed Central PMCID: PMC1630671. 4. DeSimone JA, Lyall V, Heck GL, Feldman GM. Acid detection by taste receptor cells. Respir Physiol. 2001 Dec;129(1-2):231-45. Review. PubMed PMID: 11738657.