TargetMol

Bofumustine

Product Code:
 
TAR-T26886
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26886-5mg5mg£850.00
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TAR-T26886-50mg50mg£1,661.00
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Quantity:
TAR-T26886-100mg100mg£2,079.00
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Further Information

Bioactivity:
Bofumustine is a chloroethyl nitrosourea with anti tumor properties.
CAS:
55102-44-8
Formula:
C18H21ClN4O9
Molecular Weight:
472.83
Purity:
0.98
SMILES:
CC1(C)O[C@@H]2[C@@H](COC(=O)c3ccc(cc3)[N+]([O-])=O)OC(NC(=O)N(CCCl)N=O)[C@@H]2O1

References

1. Math? G, Bothorel P. In vivo enhancement of the experimental oncostatic effect of RFCNU by its encapsulation in liposomes. Biomedicine. 1981 Dec;35(7-8):201-2. PubMed PMID: 7346064. 2. Maral R, Bourut C, Chenu E, Mathe G, Bernon R, Lussan C, Imbach JL, Schein P, Bothorel P. Comparison of the experimental antitumor activities of three nitrosourea derivatives chlorozotocin, RFCNU and CNCC encapsulated in liposomes with those in the free state. Oncology. 1985;42(2):122-8. PubMed PMID: 3157909. 3. Goden?che D, Madelmont JC, Moreau MF, Montoloy D, Plagne R. Disposition of the carcinostatic agent 1-(2-chloroethyl)-3-[1'-(5'-p-nitrobenzoyl-2',3'-isopropylidene)-alpha,beta-d-rib ofuranosyl]-1-nitrosourea in animals. Cancer Res. 1980 Sep;40(9):3351-6. PubMed PMID: 7427947. 4. Lemoine R, Gouyette A. Stability and preliminary pharmacokinetic studies of 1-(2-chloroethyl)-3-[1-(5'-paranitrobenzoyl-2',3'-isopropylidene)-alpha, beta-D-ribofuranosyl]-1-nitrosourea (RFCNU), a nonimmunosuppressive nitrosourea. Cancer Treat Rep. 1979 Aug;63(8):1335-41. PubMed PMID: 38907.