TargetMol

CAY10397

Product Code:
 
TAR-T26956
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26956-5mg5mg£850.00
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Quantity:
TAR-T26956-50mg50mg£1,661.00
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Quantity:
TAR-T26956-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
CAY10397, a selective inhibitor of 15-hydroxy PGDH, significantly suppresses endogenous 11-oxo-ETE production with a corresponding increase in 11(R)-HETE.
CAS:
78028-01-0
Formula:
C17H16N2O5
Molecular Weight:
328.324
Purity:
0.98
SMILES:
CCOC(=O)c1ccc(cc1)N=Nc1ccc(O)c(CC(O)=O)c1

References

1. Liu X, Zhang S, Arora JS, Snyder NW, Shah SJ, Blair IA. 11-Oxoeicosatetraenoic acid is a cyclooxygenase-2/15-hydroxyprostaglandin dehydrogenase-derived antiproliferative eicosanoid. Chem Res Toxicol. 2011 Dec 19;24(12):2227-36. doi: 10.1021/tx200336f. Epub 2011 Sep 30. PubMed PMID: 21916491; PubMed Central PMCID: PMC3242474. 2. Wei C, Zhu P, Shah SJ, Blair IA. 15-oxo-Eicosatetraenoic acid, a metabolite of macrophage 15-hydroxyprostaglandin dehydrogenase that inhibits endothelial cell proliferation. Mol Pharmacol. 2009 Sep;76(3):516-25. doi: 10.1124/mol.109.057489. Epub 2009 Jun 17. PubMed PMID: 19535459; PubMed Central PMCID: PMC2730384.