TargetMol

Cetocycline hydrochloride

Product Code:
 
TAR-T26984
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26984-5mg5mg£850.00
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Further Information

Bioactivity:
Cetocycline hydrochloride is an antibacterial biochemical. It is active against many clinical isolates of aerobic gram-negative bacilli, but is less active against staphylococci, and has no activity against Pseudomonas.
CAS:
56433-46-6
Formula:
C22H22ClNO7
Molecular Weight:
447.87
Purity:
0.98
SMILES:
Cl.[H][C@@]12Cc3c(C)c4ccc(C)c(O)c4c(O)c3C(=O)[C@]1(O)C(=O)C(C(C)=O)=C(O)[C@@H]2N

References

1. Proctor R, Craig W, Kunin C. Cetocycline, tetracycline analog: in vitro studies of antimicrobial activity, serum binding, lipid solubility, and uptake by bacteria. Antimicrob Agents Chemother. 1978 Apr;13(4):598-604. PubMed PMID: 666291; PubMed Central PMCID: PMC352294. 2. Stepanek JJ, Luke?i? T, Teichert I, Petkovi? H, Bandow JE. Dual mechanism of action of the atypical tetracycline chelocardin. Biochim Biophys Acta. 2016 Jun;1864(6):645-654. doi: 10.1016/j.bbapap.2016.03.004. Epub 2016 Mar 9. PubMed PMID: 26969785. 3. Le?nik U, Luke?i? T, Podgor?ek A, Horvat J, Polak T, ?ala M, Jenko B, Harmrolfs K, Ocampo-Sosa A, Mart?nez-Mart?nez L, Herron PR, Fujs ?, Kosec G, Hunter IS, M?ller R, Petkovi? H. Construction of a new class of tetracycline lead structures with potent antibacterial activity through biosynthetic engineering. Angew Chem Int Ed Engl. 2015 Mar 23;54(13):3937-40. doi: 10.1002/anie.201411028. Epub 2015 Feb 4. PubMed PMID: 25650563. 4. ?ala M, Ko?ar D, Luke?i? T, Kosec G, Hodo??ek M, Petkovi? H. Rapid identification of atypical tetracyclines using tandem mass spectrometric fragmentation patterns. Rapid Commun Mass Spectrom. 2015 Sep 15;29(17):1556-1562. doi: 10.1002/rcm.7252. PubMed PMID: 28339151.