TargetMol

Cevoglitazar

Product Code:
 
TAR-T26986
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26986-1mg1mg£157.00
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TAR-T26986-5mg5mg£279.00
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TAR-T26986-10mg10mg£384.00
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TAR-T26986-25mg25mg£595.00
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TAR-T26986-50mg50mg£816.00
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TAR-T26986-100mg100mg£1,083.00
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Quantity:
TAR-T26986-500mg500mg£2,103.00
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Further Information

Bioactivity:
Cevoglitazar is a PPAR? agonist and PPARγ agonist. Cevoglitazar potently reduces food intake and body weight in obese mice and cynomolgus monkeys.
CAS:
839673-52-8
Formula:
C27H21F3N2O6S
Molecular Weight:
558.53
Pathway:
DNA Damage/DNA Repair|Metabolism
Purity:
0.98
SMILES:
Cc1oc(nc1COc1ccc(cc1)S(=O)(=O)N1[C@H](Cc2ccccc12)C(O)=O)-c1ccc(cc1)C(F)(F)F
Target:
PPAR

References

1. Chen H, Dardik B, Qiu L, Ren X, Caplan SL, Burkey B, Boettcher BR, Gromada J. Cevoglitazar, a novel peroxisome proliferator-activated receptor-alpha/gamma dual agonist, potently reduces food intake and body weight in obese mice and cynomolgus monkeys. Endocrinology. 2010 Jul;151(7):3115-24. doi: 10.1210/en.2009-1366. PubMed PMID: 20484464. 2. Laurent D, Gounarides JS, Gao J, Boettcher BR. Effects of cevoglitazar, a dual PPARalpha/gamma agonist, on ectopic fat deposition in fatty Zucker rats. Diabetes Obes Metab. 2009 Jun;11(6):632-6. doi: 10.1111/j.1463-1326.2008.01017.x. PubMed PMID: 19175377.