TargetMol

CGP 44532

Product Code:
 
TAR-T26991
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26991-5mg5mg£850.00
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TAR-T26991-50mg50mg£1,661.00
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Quantity:
TAR-T26991-100mg100mg£2,079.00
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  • Further Information
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Further Information

Bioactivity:
CGP 44532 a GABAB receptor agonist.
CAS:
133345-68-3
Formula:
C4H12NO3P
Molecular Weight:
153.118
Purity:
0.98
SMILES:
CP(O)(=O)C[C@H](O)CN

References

1. Li X, Kaczanowska K, Finn MG, Markou A, Risbrough VB. The GABA(B) receptor positive modulator BHF177 attenuated anxiety, but not conditioned fear, in rats. Neuropharmacology. 2015 Oct;97:357-64. doi: 10.1016/j.neuropharm.2015.05.001. PubMed PMID: 26002628; PubMed Central PMCID: PMC4537349. 2. Wiero?ska JM, Kusek M, Tokarski K, Wabno J, Froestl W, Pilc A. The GABA B receptor agonist CGP44532 and the positive modulator GS39783 reverse some behavioural changes related to positive syndromes of psychosis in mice. Br J Pharmacol. 2011 Jul;163(5):1034-47. doi: 10.1111/j.1476-5381.2011.01301.x. PubMed PMID: 21371011; PubMed Central PMCID: PMC3130949. 3. Vlachou S, Paterson NE, Guery S, Kaupmann K, Froestl W, Banerjee D, Finn MG, Markou A. Both GABA(B) receptor activation and blockade exacerbated anhedonic aspects of nicotine withdrawal in rats. Eur J Pharmacol. 2011 Mar 25;655(1-3):52-8. doi: 10.1016/j.ejphar.2011.01.009. PubMed PMID: 21262222; PubMed Central PMCID: PMC3060559. 4. Partyka A, K?odzi?ska A, Szewczyk B, Wiero?ska JM, Chojnacka-W?jcik E, Librowski T, Filipek B, Nowak G, Pilc A. Effects of GABAB receptor ligands in rodent tests of anxiety-like behavior. Pharmacol Rep. 2007 Nov-Dec;59(6):757-62. PubMed PMID: 18195467.