TargetMol

CUMI-101

Product Code:
 
TAR-T27100
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27100-5mg5mg£930.00
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Quantity:
TAR-T27100-50mg50mg£1,821.00
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Quantity:
TAR-T27100-100mg100mg£2,319.00
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This product comes from: United States.
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Further Information

Bioactivity:
CUMI-101 is an agonist of 5-HT1A receptor.
CAS:
179756-61-7
Formula:
C19H27N5O3
Molecular Weight:
373.457
Purity:
0.98
SMILES:
COc1ccccc1N1CCN(CCCCn2ncc(=O)n(C)c2=O)CC1

References

1. Selvaraj S, Walker C, Arnone D, Cao B, Faulkner P, Cowen PJ, Roiser JP, Howes O. Effect of Citalopram on Emotion Processing in Humans: A Combined 5-HT(1A) [(11)C]CUMI-101 PET and Functional MRI Study. Neuropsychopharmacology. 2017 Aug 4. doi: 10.1038/npp.2017.166. [Epub ahead of print] PubMed PMID: 28776580; PubMed Central PMCID: PMC5693328. 2. Zanderigo F, Mann JJ, Ogden RT. A hybrid deconvolution approach for estimation of in vivo non-displaceable binding for brain PET targets without a reference region. PLoS One. 2017 May 1;12(5):e0176636. doi: 10.1371/journal.pone.0176636. eCollection 2017. PubMed PMID: 28459878; PubMed Central PMCID: PMC5411064. 3. Ganz M, Feng L, Hansen HD, Beliveau V, Svarer C, Knudsen GM, Greve DN. Cerebellar heterogeneity and its impact on PET data quantification of 5-HT receptor radioligands. J Cereb Blood Flow Metab. 2017 Sep;37(9):3243-3252. doi: 10.1177/0271678X16686092. Epub 2017 Jan 11. PubMed PMID: 28075185; PubMed Central PMCID: PMC5584698. 4. Schain M, Zanderigo F, Mann JJ, Ogden RT. Estimation of the binding potential BP(ND) without a reference region or blood samples for brain PET studies. Neuroimage. 2017 Feb 1;146:121-131. doi: 10.1016/j.neuroimage.2016.11.035. Epub 2016 Nov 14. PubMed PMID: 27856316.