TargetMol

Dimiracetam

Product Code:
 
TAR-T27178
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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This product comes from: United States.
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Further Information

Bioactivity:
Dimiracetam, a NMDA-receptor antagonist, is used potentially for the treatment of neuropathic pain.
CAS:
126100-97-8
Formula:
C6H8N2O2
Molecular Weight:
140.142
Purity:
0.98
SMILES:
O=C1CN2C(CCC2=O)N1

References

1. Di Cesare Mannelli L, Maresca M, Farina C, Scherz MW, Ghelardini C. A model of neuropathic pain induced by sorafenib in the rat: Effect of dimiracetam. Neurotoxicology. 2015 Sep;50:101-7. doi: 10.1016/j.neuro.2015.08.002. PubMed PMID: 26254739. 2. Fariello RG, Ghelardini C, Di Cesare Mannelli L, Bonanno G, Pittaluga A, Milanese M, Misiano P, Farina C. Broad spectrum and prolonged efficacy of dimiracetam in models of neuropathic pain. Neuropharmacology. 2014 Jun;81:85-94. doi: 10.1016/j.neuropharm.2014.01.029. PubMed PMID: 24486381. 3. Farina C, Gagliardi S, Ghelardini C, Martinelli M, Norcini M, Parini C, Petrillo P, Ronzoni S. Synthesis and biological evaluation of novel dimiracetam derivatives useful for the treatment of neuropathic pain. Bioorg Med Chem. 2008 Mar 15;16(6):3224-32. doi: 10.1016/j.bmc.2007.12.015. PubMed PMID: 18171618. 4. Torchio L, Lombardi F, Visconti M, Doyle E. Determination of the polar drug dimiracetam in human plasma and serum by column-switching high-performance liquid chromatography. J Chromatogr B Biomed Appl. 1995 Apr 7;666(1):169-77. PubMed PMID: 7655615.