TargetMol

DK-1-49

Product Code:
 
TAR-T27187
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27187-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T27187-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T27187-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
DK-1-49 is an autophagonizer. It causes accumulation of autophagy-associated LC3-II and enhanced levels of autophagosomes and acidic vacuoles.
CAS:
853136-76-2
Formula:
C28H31N5O3S2
Molecular Weight:
549.71
Purity:
0.98
SMILES:
O=C(NCCN1CCCC1)c1coc(CSc2nc3sc4CCCCc4c3c(=O)n2Cc2ccccc2)n1

References

1. Nguyen J, Chen L, Kumar D, Lee J. Facile synthesis of autophagonizer and evaluation of its activity to induce autophagic cell death in apoptosis-defective cell line. Bioorg Med Chem Lett. 2016 Oct 1;26(19):4753-6. doi: 10.1016/j.bmcl.2016.08.035. Epub 2016 Aug 13. PubMed PMID: 27597252.