TargetMol

Elasnin

Product Code:
 
TAR-T27251
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27251-5mg5mg£850.00
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Quantity:
TAR-T27251-50mg50mg£1,661.00
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Quantity:
TAR-T27251-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Elasnin is a reversible inhibitor of elastase for human granulocyte and pancreatic enzymes with IC50 values of 1.3 and 30 ?g/ml, respectively.
CAS:
68112-21-0
Formula:
C24H40O4
Molecular Weight:
392.58
Purity:
0.98
SMILES:
CCCCCC(=O)C(CCCC)c1oc(=O)c(CCCC)c(O)c1CCCC

References

1. Cook L, Ternai B, Ghosh P. Inhibition of human sputum elastase by substituted 2-pyrones. J Med Chem. 1987 Jun;30(6):1017-23. PubMed PMID: 3647139. 2. Spencer RW, Copp LJ, Pfister JR. Inhibition of human leukocyte elastase, porcine pancreatic elastase, and chymotrypsin by elasnin and other 4-hydroxy-2-pyrones. J Med Chem. 1985 Dec;28(12):1828-32. PubMed PMID: 4068006. 3. Groutas WC, Stanga MA, Brubaker MJ, Huang TL, Moi MK, Carroll RT. Substituted 2-pyrones, 2-pyridones, and other congeners of elasnin as potential agents for the treatment of chronic obstructive lung diseases. J Med Chem. 1985 Aug;28(8):1106-9. PubMed PMID: 3848491. 4. Ohno H, Yoshida M, Takahashi Y, Omura S. Improvement of the productivity of elasnin, a specific elastase inhibitor, by Streptomyces noboritoensis KM-2753. J Antibiot (Tokyo). 1980 May;33(5):474-9. PubMed PMID: 6903571.