TargetMol

Emitefur

Product Code:
 
TAR-T27259
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27259-5mg5mg£790.00
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TAR-T27259-50mg50mg£1,661.00
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Quantity:
TAR-T27259-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Emitefur is a 5-fluorouracil derivative antitumor drug.
CAS:
110690-43-2
Formula:
C28H19FN4O8
Molecular Weight:
558.478
Purity:
0.98
SMILES:
CCOCn1cc(F)c(=O)n(C(=O)c2cccc(c2)C(=O)Oc2nc(OC(=O)c3ccccc3)ccc2C#N)c1=O

References

1. Shibahara T, Kaneko E, Itoh T, Awogi T, Tsushimoto G, Takahashi N, Marshall RR, Kirkland DJ. Mutagenic and clastogenic properties of (3-[3-(6-benzoyloxy-3-cyano-2- pyridyloxycarbonyl) benzoyl]-1-ethoxymethyl-5-fluorouracil) (BOF-A2), a new 5-fluorouracil derivative with anti-tumour activity. J Toxicol Sci. 1993 Aug;18 Suppl 3:11-9. PubMed PMID: 8258847. 2. Sugimachi K, Maehara Y. A phase II trial of a new 5-fluorouracil derivative, BOF-A2 (Emitefur), for patients with advanced gastric cancer. Surg Today. 2000;30(12):1067-72. PubMed PMID: 11193737. 3. Shibamoto Y, Murata R, Miyauchi S, Hirohashi M, Takagi T, Sasai K, Shibata T, Oya N, Takahashi M. Combined effect of clinically relevant doses of emitefur, a new 5-fluorouracil derivative, and radiation in murine tumours. Br J Cancer. 1996 Dec;74(11):1709-13. PubMed PMID: 8956782; PubMed Central PMCID: PMC2077217. 4. Fujita F, Fujita M, Sakamoto Y, Taguchi T. [Antitumor activity of combination treatment of BOF-A2 with CDDP against human lung cancers xenografted in nude mice]. Gan To Kagaku Ryoho. 1993 Feb;20(2):215-21. Japanese. PubMed PMID: 8382036.