TargetMol

Fidexaban

Product Code:
 
TAR-T27318
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27318-1mg1mg£185.00
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TAR-T27318-5mg5mg£360.00
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TAR-T27318-10mg10mg£496.00
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TAR-T27318-25mg25mg£760.00
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Quantity:
TAR-T27318-50mg50mg£1,018.00
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Quantity:
TAR-T27318-100mg100mg£1,348.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Fidexaban, a coagulation factor and Xa inhibitor, is used potentially for the treatment of angina pectoris.
CAS:
183305-24-0
Formula:
C25H24F2N6O5
Molecular Weight:
526.501
Pathway:
Metabolism
Purity:
0.98
SMILES:
CN(CC(O)=O)c1c(F)c(Oc2cccc(c2)C2=NCCN2C)nc(Oc2cc(ccc2O)C(N)=N)c1F
Target:
Factor Xa

References

1. Remko M, Remkov? A, Broer R. Theoretical Study of Molecular Structure and Physicochemical Properties of Novel Factor Xa Inhibitors and Dual Factor Xa and Factor IIa Inhibitors. Molecules. 2016 Feb 4;21(2). pii: E185. doi: 10.3390/molecules21020185. PubMed PMID: 26861270. 2. Doggrell SA. Is there evidence to support the use of direct Factor Xa inhibitors in coronary artery disease? Rev Recent Clin Trials. 2011 May;6(2):147-57. Review. PubMed PMID: 21241235. 3. Zafar MU, Farkouh ME, Osende J, Shimbo D, Palencia S, Crook J, Leadley R, Fuster V, Chesebro JH. Potent arterial antithrombotic effect of direct factor-Xa inhibition with ZK-807834 administered to coronary artery disease patients. Thromb Haemost. 2007 Mar;97(3):487-92. PubMed PMID: 17334518. 4. Karnicki K, McBane RD 2nd, Miller RS, Leadley RJ Jr, Morser J, Owen WG, Chesebro JH. Inhibition and reversal of platelet-rich arterial thrombus in vivo: direct vs. indirect factor Xa inhibition. J Thromb Haemost. 2004 Dec;2(12):2162-9. PubMed PMID: 15613022.