TargetMol

Floctafenine

Product Code:
 
TAR-T27335
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27335-5mg5mg£850.00
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TAR-T27335-50mg50mg£1,661.00
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Quantity:
TAR-T27335-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Floctafenine, a cyclooxygenase inhibitor, inhibits the synthesis of prostaglandin.
CAS:
23779-99-9
Formula:
C20H17F3N2O4
Molecular Weight:
406.361
Purity:
0.98
SMILES:
OCC(O)COC(=O)c1ccccc1Nc1ccnc2c(cccc12)C(F)(F)F

References

1. Maenthaisong R, Tacconelli S, Sritara P, Del Boccio P, Di Francesco L, Sacchetta P, Archararit N, Aryurachai K, Patrignani P, Suthisisang C. Clinical pharmacology of cyclooxygenase inhibition and pharmacodynamic interaction with aspirin by floctafenine in Thai healthy subjects. Int J Immunopathol Pharmacol. 2013 Apr-Jun;26(2):403-17. PubMed PMID: 23755755. 2. Walash MI, Belal F, El-Enany N, Eid M, El-Shaheny RN. Simultaneous determination of floctafenine and its hydrolytic degradation product floctafenic acid using micellar liquid chromatography with applications to tablets and human plasma. J AOAC Int. 2013 Nov-Dec;96(6):1315-24. PubMed PMID: 24645510. 3. Walash M, Belal F, Eid M, el-Abass SA. Simultaneous HPLC determination of thiocolchicoside and glafenine as well as thiocolchicoside and floctafenine in their combined dosage forms. J Chromatogr Sci. 2011 Feb;49(2):159-64. PubMed PMID: 21223643. 4. Giuseppe P, Antonino R, Alessandro DB, Donato Q, Marina DF, Donatella P, Francesca G, Alberto V. Floctafenine: a valid alternative in patients with adverse reactions to nonsteroidal anti-inflammatory drugs. Ann Allergy Asthma Immunol. 1997 Jan;78(1):74-8. PubMed PMID: 9012626.