TargetMol

Floxacrine

Product Code:
 
TAR-T27337
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27337-5mg5mg£850.00
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TAR-T27337-50mg50mg£1,661.00
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Quantity:
TAR-T27337-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Floxacrine is drug candidate for chemoprophylaxis of malaria.
CAS:
53966-34-0
Formula:
C20H13ClF3NO3
Molecular Weight:
407.77
Purity:
0.98
SMILES:
On1c2CC(CC(=O)c2c(=O)c2cc(Cl)ccc12)c1ccc(cc1)C(F)(F)F

References

1. Cross RM, Maignan JR, Mutka TS, Luong L, Sargent J, Kyle DE, Manetsch R. Optimization of 1,2,3,4-tetrahydroacridin-9(10H)-ones as antimalarials utilizing structure-activity and structure-property relationships. J Med Chem. 2011 Jul 14;54(13):4399-426. doi: 10.1021/jm200015a. Epub 2011 Jun 16. PubMed PMID: 21630666. 2. Milhous W. Development of new drugs for chemoprophylaxis of malaria. Bull Soc Pathol Exot. 2001 Jul;94(2 Pt 2):149-51. PubMed PMID: 16579068. 3. Milhous WK. Development of new drugs for chemoprophylaxis of malaria. Med Trop (Mars). 2001;61(1):48-50. Review. PubMed PMID: 11584654. 4. Dorn A, Scovill JP, Ellis WY, Matile H, Ridley RG, Vennerstrom JL. Short report: floxacrine analog WR 243251 inhibits hematin polymerization. Am J Trop Med Hyg. 2001 Jul;65(1):19-20. PubMed PMID: 11504401.