TargetMol

Fozivudine tidoxil

Product Code:
 
TAR-T27354
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27354-5mg5mg£850.00
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TAR-T27354-50mg50mg£1,661.00
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Quantity:
TAR-T27354-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Fozivudine tidoxil, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.
CAS:
141790-23-0
Formula:
C35H64N5O8PS
Molecular Weight:
745.96
Purity:
0.98
SMILES:
CCCCCCCCCCCCSC[C@@H](COP(O)(=O)OC[C@H]1O[C@H](C[C@@H]1N=[N+]=[N-])n1cc(C)c(=O)[nH]c1=O)OCCCCCCCCCC

References

1. Miller MM, Fogle JE. Administration of Fozivudine tidoxil as a single-agent therapeutic during acute feline immunodeficiency virus infection does not alter chronic infection. Viruses. 2012 Jun;4(6):954-62. doi: 10.3390/v4060954. PubMed PMID: 22816034; PubMed Central PMCID: PMC3397356. 2. Fogle JE, Tompkins WA, Campbell B, Sumner D, Tompkins MB. Fozivudine tidoxil as single-agent therapy decreases plasma and cell-associated viremia during acute feline immunodeficiency virus infection. J Vet Intern Med. 2011 May-Jun;25(3):413-8. doi: 10.1111/j.1939-1676.2011.0699.x. PubMed PMID: 21457319; PubMed Central PMCID: PMC3785110. 3. Venhoff AC, Lebrecht D, Reuss FU, Heckl-Ostreicher B, Wehr R, Walker UA, Venhoff N. Mitochondrial DNA depletion in rat liver induced by fosalvudine tidoxil, a novel nucleoside reverse transcriptase inhibitor prodrug. Antimicrob Agents Chemother. 2009 Jul;53(7):2748-51. doi: 10.1128/AAC.00364-09. PubMed PMID: 19433557; PubMed Central PMCID: PMC2704664. 4. Fozivudine: BM 211290, fozivudine tidoxil, FZT, HDP 990002, W 09726867. Drugs R D. 2004;5(1):41-3. Review. PubMed PMID: 14725491.