TargetMol

FPL-62129

Product Code:
 
TAR-T27357
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27357-5mg5mg£850.00
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Quantity:
TAR-T27357-50mg50mg£1,661.00
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Quantity:
TAR-T27357-100mg100mg£2,079.00
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Further Information

Bioactivity:
FPL-62129 is a calcium channel antagonist. FPL-62129 reduced blood pressure without altering heart rate. FPL 62129 showed marked activity at the sinus node and to a lesser extent at the atrioventricular node. FPL 62129 lowers blood pressure without causing reflex tachycardia in this model.
CAS:
95445-79-7
Formula:
C20H19ClF5NO4
Molecular Weight:
467.82
Purity:
0.98
SMILES:
COC(=O)C1=C(CF)NC(C)=C(C1c1c(F)ccc(Cl)c1C(F)(F)F)C(=O)OC(C)C

References

1. Humphries RG, O'Connor SE. Cardiovascular profile of FPL 62129, a novel dihydropyridine calcium channel blocker, in anaesthetised dogs: a comparison with nifedipine. J Cardiovasc Pharmacol. 1988 Mar;11(3):332-8. PubMed PMID: 2452927.