TargetMol

GNE-293

Product Code:
 
TAR-T27422
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27422-5mg5mg£850.00
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Quantity:
TAR-T27422-50mg50mg£1,661.00
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Quantity:
TAR-T27422-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
GNE-293 is a potent and selective PI3Kδ inhibitor.
CAS:
1354955-67-1
Formula:
C28H36N8O4S
Molecular Weight:
580.71
Purity:
0.98
SMILES:
CC(C)c1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(OC3CN(C3)C3CCS(=O)(=O)CC3)n(C)c2n1

References

1. Safina BS, Sweeney ZK, Li J, Chan BK, Bisconte A, Carrera D, Castanedo G, Flagella M, Heald R, Lewis C, Murray JM, Nonomiya J, Pang J, Price S, Reif K, Salphati L, Seward EM, Wei B, Sutherlin DP. Identification of GNE-293, a potent and selective PI3K? inhibitor: navigating in vitro genotoxicity while improving potency and selectivity. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4953-9. doi: 10.1016/j.bmcl.2013.06.052. Epub 2013 Jun 29. PubMed PMID: 23867164.