TargetMol

GS 389

Product Code:
 
TAR-T27436
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27436-5mg5mg£850.00
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TAR-T27436-50mg50mg£1,661.00
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TAR-T27436-100mg100mg£2,079.00
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Further Information

Bioactivity:
GS 389 is a novel tetrahydroisoquinoline analog with vasorelaxant properties. GS-389 significantly inhibited cGMP phosphodiesterase from the rabbit brain and increased cGMP levels in the rat aorta.
CAS:
41498-37-7
Formula:
C19H23NO3
Molecular Weight:
313.397
Purity:
0.98
SMILES:
COc1ccc(CC2NCCc3cc(OC)c(OC)cc23)cc1

References

1. Chang KC, Chong WS, Lee IJ. Different pharmacological characteristics of structurally similar benzylisoquinoline analogs, papaverine, higenamine, and GS 389, on isolated rat aorta and heart. Can J Physiol Pharmacol. 1994 Apr;72(4):327-34. PubMed PMID: 7922863. 2. Chang KC, Lim JK, Park CW. Pharmacological evaluation of GS-389, a novel tetrahydroisoquinoline analog related to higenamine, on vascular smooth muscle. Life Sci. 1992;51(1):67-74. PubMed PMID: 1614275.