TargetMol

GS-9851

Product Code:
 
TAR-T27440
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27440-5mg5mg£1,412.00
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Quantity:
TAR-T27440-50mg50mg£2,785.00
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Quantity:
TAR-T27440-100mg100mg£3,765.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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  • Further Information
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Further Information

Bioactivity:
GS-9851, a HCV nonstructural protein 5B (NS5B) inhibitor, is used potentially for the treatment of HCV infection.
CAS:
1064684-44-1
Formula:
C22H29FN3O9P
Molecular Weight:
529.46
Purity:
0.98
SMILES:
C[C@@H](C(OC(C)C)=O)NP(OC[C@@H]1[C@H]([C@@](C)(F)[C@H](N2C(NC(C=C2)=O)=O)O1)O)(OC3=CC=CC=C3)=O

References

1. Lawitz E, Rodriguez-Torres M, Denning JM, Albanis E, Cornpropst M, Berrey MM, Symonds WT. Pharmacokinetics, pharmacodynamics, and tolerability of GS-9851, a nucleotide analog polymerase inhibitor, following multiple ascending doses in patients with chronic hepatitis C infection. Antimicrob Agents Chemother. 2013 Mar;57(3):1209-17. doi: 10.1128/AAC.01263-12. Epub 2012 Dec 21. PubMed PMID: 23263000; PubMed Central PMCID: PMC3591915. 2. Denning J, Cornpropst M, Flach SD, Berrey MM, Symonds WT. Pharmacokinetics, safety, and tolerability of GS-9851, a nucleotide analog polymerase inhibitor for hepatitis C virus, following single ascending doses in healthy subjects. Antimicrob Agents Chemother. 2013 Mar;57(3):1201-8. doi: 10.1128/AAC.01262-12. Epub 2012 Dec 21. PubMed PMID: 23262999; PubMed Central PMCID: PMC3591883.