TargetMol

H77-77

Product Code:
 
TAR-T27523
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27523-5mg5mg£850.00
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Quantity:
TAR-T27523-50mg50mg£1,661.00
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Quantity:
TAR-T27523-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
H77-77, a monoamine oxidase (MAO) inhibitor, produces a pronounced protection against phenelzine within the serotonergic and noradrenergic neurons in rats.
CAS:
21618-99-5
Formula:
C10H15NO
Molecular Weight:
165.236
Purity:
0.98
SMILES:
CC(N)Cc1ccc(C)c(O)c1

References

1. Fagervall I, Kelder D, Ross SB. Selective inhibition by 4,alpha-dimethyl-m-tyramine (H77/77) and 4-methyl-alpha-ethyl-m-tyramine (H75/12) of the monoamine oxidase within serotonergic and noradrenergic neurons in the rat brain. Naunyn Schmiedebergs Arch Pharmacol. 1988 Aug;338(2):143-7. PubMed PMID: 2460774. 2. Fuxe K, Janson AM, Ros?n L, Finnman UB, Tanganelli S, Morari M, Goldstein M, Agnati LF. Evidence for a protective action of the vigilance promoting drug modafinil on the MPTP-induced degeneration of the nigrostriatal dopamine neurons in the black mouse: an immunocytochemical and biochemical analysis. Exp Brain Res. 1992;88(1):117-30. PubMed PMID: 1347270. 3. Leonard BE, Shallice SA. Some neurochemical effects of amphetamine, methylamphetamine and p-bromomethylamphetamine in the rat. Br J Pharmacol. 1971 Feb;41(2):198-212. PubMed PMID: 5572273; PubMed Central PMCID: PMC1703283. 4. Maj J, Melzacka M, Mogilnicka E, Daniel W. Different pharmacokinetic and pharmacological effects following acute and chronic treatment with imipramine. J Neural Transm. 1982;54(3-4):219-28. PubMed PMID: 7130974.