TargetMol

Icofungipen

Product Code:
 
TAR-T27580
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27580-5mg5mg£1,010.00
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TAR-T27580-50mg50mg£1,982.00
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Quantity:
TAR-T27580-100mg100mg£2,560.00
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This product comes from: United States.
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Further Information

Bioactivity:
Icofungipen is an oral antifungals with active against Candida species.
CAS:
198022-65-0
Formula:
C7H11NO2
Molecular Weight:
141.17
Purity:
0.98
SMILES:
N[C@H]1CC(=C)C[C@H]1C(O)=O

References

1. Kiss L, Forr? E, Orsy G, ?brah?mi R, F?l?p F. Stereo- and Regiocontrolled Syntheses of Exomethylenic Cyclohexane ?-Amino Acid Derivatives. Molecules. 2015 Nov 27;20(12):21094-102. doi: 10.3390/molecules201219749. PubMed PMID: 26633314. 2. Novak P, Tepes P, Ilijas M, Fistri? I, Bratos I, Avdagi? A, Hamersak Z, Markovi? VG, Dumi? M. LC-NMR and LC-MS identification of an impurity in a novel antifungal drug icofungipen. J Pharm Biomed Anal. 2009 Aug 15;50(1):68-72. doi: 10.1016/j.jpba.2009.03.017. Epub 2009 Mar 25. PubMed PMID: 19410412. 3. Ferrer E. Spotlight on targeting aminoacyl-tRNA synthetases for the treatment of fungal infections. Drug News Perspect. 2006 Jul-Aug;19(6):347-8. PubMed PMID: 16971970. 4. Hasenoehrl A, Galic T, Ergovic G, Marsic N, Skerlev M, Mittendorf J, Geschke U, Schmidt A, Schoenfeld W. In vitro activity and in vivo efficacy of icofungipen (PLD-118), a novel oral antifungal agent, against the pathogenic yeast Candida albicans. Antimicrob Agents Chemother. 2006 Sep;50(9):3011-8. PubMed PMID: 16940096; PubMed Central PMCID: PMC1563551.