TargetMol

KB-141

Product Code:
 
TAR-T27714
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27714-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T27714-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T27714-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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  • Further Information
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Further Information

Bioactivity:
KB-141 is an agonist of thyroid hormone receptor.
CAS:
219691-94-8
Formula:
C17H16Cl2O4
Molecular Weight:
355.21
Purity:
0.98
SMILES:
CC(C)c1cc(Oc2c(Cl)cc(CC(O)=O)cc2Cl)ccc1O

References

1. Shi C, Meng Q, Wood DW. Analysis of the roles of mutations in thyroid hormone receptor-? by a bacterial biosensor system. J Mol Endocrinol. 2014 Jan 8;52(1):55-66. doi: 10.1530/JME-13-0108. PubMed PMID: 24174637. 2. T?th G, Nosz?l B. [Thyroid hormones and their precursors I. Biochemical properties]. Acta Pharm Hung. 2013;83(2):35-45. Review. Hungarian. PubMed PMID: 23926648. 3. Gierach I, Li J, Wu WY, Grover GJ, Wood DW. Bacterial biosensors for screening isoform-selective ligands for human thyroid receptors ?-1 and ?-1. FEBS Open Bio. 2012 Aug 15;2:247-53. doi: 10.1016/j.fob.2012.08.002. PubMed PMID: 23667826; PubMed Central PMCID: PMC3642162. 4. Tancevski I, Eller P, Patsch JR, Ritsch A. The resurgence of thyromimetics as lipid-modifying agents. Curr Opin Investig Drugs. 2009 Sep;10(9):912-8. Review. PubMed PMID: 19705333; PubMed Central PMCID: PMC2993058.