TargetMol

KF 17837S

Product Code:
 
TAR-T27727
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27727-5mg5mg£850.00
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Quantity:
TAR-T27727-50mg50mg£1,661.00
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Quantity:
TAR-T27727-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
KF 17837S is an adenosine A(2a) receptor antagonists.
CAS:
152881-18-0
Formula:
C20H26N4O4
Molecular Weight:
386.452
Purity:
0.98
SMILES:
CCCn1c2nc(-c3ccc(OC)c(OC)c3)n(C)c2c(=O)n(CCC)c1=O

References

1. Morelli M, Wardas J. Adenosine A(2a) receptor antagonists: potential therapeutic and neuroprotective effects in Parkinson's disease. Neurotox Res. 2001 Nov;3(6):545-56. PubMed PMID: 15111244. 2. Correa M, Wisniecki A, Betz A, Dobson DR, O'Neill MF, O'Neill MJ, Salamone JD. The adenosine A2A antagonist KF17837 reverses the locomotor suppression and tremulous jaw movements induced by haloperidol in rats: possible relevance to parkinsonism. Behav Brain Res. 2004 Jan 5;148(1-2):47-54. PubMed PMID: 14684247. 3. Bivalacqua TJ, Champion HC, Lambert DG, Kadowitz PJ. Vasodilator responses to adenosine and hyperemia are mediated by A(1) and A(2) receptors in the cat vascular bed. Am J Physiol Regul Integr Comp Physiol. 2002 Jun;282(6):R1696-709. PubMed PMID: 12010752.