TargetMol

KRP-101

Product Code:
 
TAR-T27746
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27746-5mg5mg£1,091.00
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Quantity:
TAR-T27746-50mg50mg£2,143.00
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Quantity:
TAR-T27746-100mg100mg£2,801.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
KRP-101, a PPAR? agonist, is used potentially for the treatment of diabetes and hyperlipidaemia.
CAS:
311770-26-0
Formula:
C26H26FNO5
Molecular Weight:
451.494
Purity:
0.98
SMILES:
CC[C@@H](Cc1ccc(OC)c(c1)C(=O)N(C)c1ccc(Oc2ccc(F)cc2)cc1)C(O)=O

References

1. Nagasawa M, Hara T, Kashino A, Akasaka Y, Ide T, Murakami K. Identification of a functional peroxisome proliferator-activated receptor (PPAR) response element (PPRE) in the human apolipoprotein A-IV gene. Biochem Pharmacol. 2009 Sep 1;78(5):523-30. doi: 10.1016/j.bcp.2009.05.007. PubMed PMID: 19433068. 2. Tsunoda M, Kobayashi N, Ide T, Utsumi M, Nagasawa M, Murakami K. A novel PPARalpha agonist ameliorates insulin resistance in dogs fed a high-fat diet. Am J Physiol Endocrinol Metab. 2008 May;294(5):E833-40. doi: 10.1152/ajpendo.00627.2007. PubMed PMID: 18212024. 3. Nagasawa M, Akasaka Y, Ide T, Hara T, Kobayashi N, Utsumi M, Murakami K. Highly sensitive upregulation of apolipoprotein A-IV by peroxisome proliferator-activated receptor alpha (PPARalpha) agonist in human hepatoma cells. Biochem Pharmacol. 2007 Dec 15;74(12):1738-46. PubMed PMID: 17904533.