TargetMol

L-162,313

Product Code:
 
TAR-T27762
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27762-1mg1mg£352.00
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Quantity:
TAR-T27762-5mg5mg£736.00
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TAR-T27762-10mg10mg£978.00
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TAR-T27762-25mg25mg£1,348.00
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Quantity:
TAR-T27762-50mg50mg£1,661.00
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Quantity:
TAR-T27762-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
L-162,313 is an agonist of AT1 receptor.
CAS:
151488-11-8
Formula:
C30H38N4O4S2
Molecular Weight:
582.78
Pathway:
Endocrinology/Hormones
Purity:
0.98
SMILES:
CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1
Target:
RAAS

References

1. Steckelings UM, Larhed M, Hallberg A, Widdop RE, Jones ES, Wallinder C, Namsolleck P, Dahl?f B, Unger T. Non-peptide AT2-receptor agonists. Curr Opin Pharmacol. 2011 Apr;11(2):187-92. doi: 10.1016/j.coph.2010.11.002. Review. PubMed PMID: 21167778. 2. Wu X, Kihara T, Hongo H, Akaike A, Niidome T, Sugimoto H. Angiotensin receptor type 1 antagonists protect against neuronal injury induced by oxygen-glucose depletion. Br J Pharmacol. 2010 Sep;161(1):33-50. doi: 10.1111/j.1476-5381.2010.00840.x. PubMed PMID: 20718738; PubMed Central PMCID: PMC2962815. 3. Tadevosyan A, Maguy A, Villeneuve LR, Babin J, Bonnefoy A, Allen BG, Nattel S. Nuclear-delimited angiotensin receptor-mediated signaling regulates cardiomyocyte gene expression. J Biol Chem. 2010 Jul 16;285(29):22338-49. doi: 10.1074/jbc.M110.121749. PubMed PMID: 20463030; PubMed Central PMCID: PMC2903375.