TargetMol

Lapisteride

Product Code:
 
TAR-T27798
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T27798-1mg1mg£135.00
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TAR-T27798-5mg5mg£215.00
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TAR-T27798-10mg10mg£279.00
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TAR-T27798-25mg25mg£477.00
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TAR-T27798-50mg50mg£617.00
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TAR-T27798-100mg100mg£848.00
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Quantity:
TAR-T27798-500mg500mg£1,621.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Lapisteride is a steroid 5α-reductase inhibitor. CS-891 inhibits 5aR activity in dermal papillae (DP) of human HF. The local conversion of testosterone (T) to the more potent androgen dihydrotestosterone (DHT) by 5alpha-reductase (5aR) is implicated in the pathogenesis of androgenetic alopecia (AGA).
CAS:
142139-60-4
Formula:
C29H40N2O3
Molecular Weight:
464.65
Purity:
0.98
SMILES:
[H][C@@]12CC[C@H](C(=O)NC(C)(C)c3ccc(OC)cc3)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])NC(=O)C=C[C@]12C

References

1. Yada S, Ohya M, Ohuchi Y, Hamaura T, Wakiyama N, Usui F, Kusai A, Yamamoto K. Solid phase transition of CS-891 enantiotropes during grinding. Int J Pharm. 2003 Apr 14;255(1-2):69-79. PubMed PMID: 12672603. 2. Niiyama S, Kojima K, Hamada T, Happle R, Hoffmann R. The novel drug CS-891 inhibits 5alpha-reductase activity in freshly isolated dermal papilla of human hair follicles. Eur J Dermatol. 2000 Dec;10(8):593-5. PubMed PMID: 11125319.